Fig. 5
From: White matter is increased in the brains of adults with neurofibromatosis 1
Correlation matrix of brain volume measurements with clinical and neuropsychometric assessments in adults with NF1. The color of each circle represents the degree of correlation from strongly negative (− 1, red) to strongly positive (+ 1, blue), as shown on the vertical scale on the right side of the figure. The size of the circles also indicates the strength of the correlation, with values closer to − 1 or + 1 larger than those that are closer to 0. Asterisks indicate FDR-adjusted statistical significance based on n = 16–19. *p < 0.05, **p < 0.01, ***p < 0.001. Abbreviations: Clin. Sev. = Riccardi clinical NF1 severity score, Neuro. Sev. = clinical neurological severity score, ADD/ADHD = clinical Attention deficit hyperactivity disorder severity score, IQ = intelligence quotient, ACS = Attention Comparison Score, L = left, R = right, GM = grey matter volume, WM = white matter volume, CC = corpus callosum, BS = brainstem, and HC = hippocampus without subiculum