Fig. 3

A 44-year-old patient with posterior sympathetic ophthalmia (PSO) accompanied by multifocal choroiditis. Fundus photography, fundus fluorescein angiography (FFA) and optical coherence tomography (OCT) images of the right eye (sympathizing eye). a-d Acute stage. a The fundus photograph shows yellow-white infiltrations in the macular and peripapillary areas that are accompanied by vitritis. b Early phase FFA shows choroidal hypofluorescent spots. c Late phase FFA shows fluorescence staining of the inflammatory lesions. d The OCT image shows inflammatory lesions on the retinal pigment epithelium (RPE; arrows) that protrude into the outer layer of the retina. The initial Snellen visual acuity was 20/400. e, f Fifteen months after treatment. f The OCT image shows shrinkage and hyperreflective fibrosis of the inflammatory lesions (arrows). The OCT image shows extensive loss of the external limiting membrane and ellipsoid zone, together with extensive atrophy of the RPE. The final Snellen visual acuity was maintained at 20/400