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Table 1 Demographics and clinical baseline characteristics of the two subgroups

From: Biochemical algorithm to identify individuals with ALPL variants among subjects with persistent hypophosphatasaemia

 

+GT (n = 40)

−GT (n = 37)

p value

Caucasian race, n (%)

39 (97.5)

37 (100%)

0.8

Median age (IQR), years

52.8 (38.8–61.2)

46.6 (40.1–49.9)

0.2

Female sex, n (%)

27 (67.5%)

32 (86.8%)

0.05

Median BMI (IQR), kg/m2

25.2 (23–29)

22.6 (20.6–24.6)

 < 0.01

Musculoskeletal pain, n (%)

28 (70%)

18 (48.6%)

 < 0.05

Dental abnormalities, n (%)

16 (40%)

4 (11%)

 < 0.001

Premature teeth loss or multiple extractions, n (%)

3 (7.5%)

1 (2.7%)

0.3

Calcific periarthritis, n (%)

7 (18%)

4 (10.8%)

0.4

PH of fractures, n (%)

16 (40%)

14 (37.8%)

0.5

PH of stress fractures, n (%)

6 (15%)

1 (2.7%)

0.06

  1. Significant values are shown in bold
  2. +GT positive genetic test, −GT negative genetic test, PH personal history