Fig. 2From: Genetic mutation spectrum of pantothenate kinase-associated neurodegeneration expanded by breakpoint sequencing in pantothenate kinase 2 geneBreakpoint mapping and characterization of the PANK2 exon 3–4 deletion. A Schematic representation of 5016 bp deletion breakpoints. B Sequence analysis showing breakpoints of the exon 3–4 large deletion. Breakpoints of this deletion are inside Alu repeats indicating Alu-mediated homologous recombination. C Sequence alignment at deletion breakpoints. Boxes indicate the Alu-sequence homologyBack to article page