Concordance between the schedule for the evaluation of individual quality of life-direct weighting (SEIQoL-DW) and the EuroQoL-5D (EQ-5D) measures of quality of life outcomes in adults with X-linked hypophosphatemia

Table 2 Change in QoL of adult XLH Patients over 12 months and at 3-month intervals using EQ-5D, SEIQoL_{baseline_cues}, SEIQoL_{visit_cues}

Instrument	Visit comparison	Estimates of mean differences	p-value*
EQ-5D	M3 versus baseline	1.57	0.999
	M6 versus M3	− 10.73	0.037*
	M9 versus M6	6.68	0.105
	M12 versus M9	− 0.22	0.999
SEIQoL-DW (baseline cues)	M3 versus baseline	− 3.78	0.77
	M6 versus M3	− 10.95	0.131
	M9 versus M6	12.48	0.049*
	M12 versus M9	− 5.06	0.322
SEIQoL-DW (visit cues)	M3 versus baseline	− 2.89	0.275
	M6 versus M3	− 12.32	0.084
	M9 versus M6	7.52	0.084
	M12 versus M9	− 5.67	0.155
Overall	EQ-5D M12 versus EQ-5D baseline	− 2.7	0.375
	SEIQoL_{baseline_cues} M12 versus SEIQoL_{baseline_cues} baseline	− 7.32	0.232
	SEIQoL_{visit_cues} M12 versus SEIQoL_{baseline_cues} baseline	− 13.36	0.037*

ISSN: 1750-1172