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Table 4 Total HCRU for DM and cDM cohorts compared to matched controls for 12-month Follow-up Period, broken down by resource type

From: Healthcare resource utilization, total costs, and comorbidities among patients with myotonic dystrophy using U.S. insurance claims data from 2012 to 2019

Resource use

DM cohort (n = 8390)

Non-DM control cohort (n = 8297)

 

cDM cohort (n = 236)

Non-cDM control cohort (n = 228)

 

N (%)

Mean (SD)

Median

N (%)

Mean (SD)

Median

p value

N (%)

Mean (SD)

Median

N (%)

Mean (SD)

Median

p value

Outpatient pharmacy (in Rx)

Patients with ≥ 1 pharmacy record

8388 (100)

  

8292 (99.9)

  

0.4142

236 (100)

  

228 (100)

  

Prescription fills per patient

 

34.88 (34.78)

24

 

29.46 (32.28)

19

 < .0001

 

15.45 (17.03)

10

 

7.30 (7.20)

5

 < .0001

Outpatient medical (in Dx)

Patients with ≥ 1 outpatient visit

8381 (99.9)

  

8258 (99.5)

  

 < .0001

236 (100)

  

223 (97.8)

  

 < .0001

Number of outpatient visits per patient

 

26.78 (42.40)

15

 

12.23 (20.35)

7

 < .0001

 

70.01 (82.77)

42

 

8.21 (7.13)

7

 < .0001

Physician office visits

Patients with ≥ 1 physician office visit

7346 (87.6)

  

6880 (82.9)

  

 < .0001

196 (83.1)

  

188 (82.5)

  

0.8907

Number of physician office visits per patient

 

8.41 (10.40)

5

 

6.10 (9.23)

4

 < .0001

 

11.25 (13.95)

7.5

 

5.86 (5.42)

5

 < .0001

ER visits

Patients with ≥ 1 ER visit

2536 (30.2)

  

1815 (21.9)

  

 < .0001

110 (46.6)

  

78 (34.2)

  

0.0080

Number of ER visits per patient

 

0.73 (2.31)

0

 

0.45 (1.33)

0

 < .0001

 

1.33 (2.96)

0

 

0.64 (1.31)

0

0.0003

Inpatient hospitalizations (In subset with linkage to Charge Description Master)

Patients with ≥ 1 hospitalization

247 (2.9)

  

160 (1.9)

  

 < .0001

18 (7.6)

  

3 (1.3)

  

0.0010

Number of hospitalizations per patient

 

0.05 (0.35)

0

 

0.03 (0.24)

0

 < .0001

 

0.11 (0.50)

0

 

0.02 (0.22)

0

0.0032