Table 1 The enriched gene ontology terms for neutrophil-associated DEGs
Term | Description | Count | Genes | P value |
|---|---|---|---|---|
GO:1990266 | Neutrophil migration | 10 | C3AR1, CCL11, CCL15, CCL20, CCL7, CXCL5, DAPK2, PDE4B, UMOD, XG | 7.33E−15 |
GO:0030593 | Neutrophil chemotaxis | 8 | C3AR1, CCL11, CCL15, CCL20, CCL7, CXCL5, DAPK2, PDE4B | 8.57E−12 |
GO:0072677 | Eosinophil migration | 5 | CCL11, CCL15, CCL7, DAPK2, EPX | 1.05E−09 |
GO:0008009 | Chemokine activity | 5 | CCL11, CCL15, CCL20, CCL7, CXCL5 | 2.25E−08 |
GO:0048245 | Eosinophil chemotaxis | 4 | CCL11, CCL15, CCL7, DAPK2 | 7.79E−08 |
GO:2000403 | Positive regulation of lymphocyte migration | 3 | CCL20, CCL7, PYCARD | 3.68E−05 |
GO:1902624 | Positive regulation of neutrophil migration | 3 | C3AR1, DAPK2, XG | 2.89E−05 |
GO:1902622 | Regulation of neutrophil migration | 3 | C3AR1, DAPK2, XG | 6.48E−05 |
GO:2000406 | Positive regulation of T cell migration | 2 | CCL20, PYCARD | 0.0012951 |
GO:2000144 | Positive regulation of DNA-templated transcription, initiation | 2 | CAND1, PSMC3 | 0.0012951 |
GO:0090023 | Positive regulation of neutrophil chemotaxis | 2 | C3AR1, DAPK2 | 0.0011382 |
GO:0070944 | Neutrophil-mediated killing of bacterium | 2 | AZU1, ELANE | 5.63E−05 |
GO:0060261 | Positive regulation of transcription initiation from RNA polymerase II promoter | 2 | CAND1, PSMC3 | 7.89E−04 |
GO:0060260 | Regulation of transcription initiation from RNA polymerase II promoter | 2 | CAND1, PSMC3 | 0.0013772 |
GO:0051123 | RNA polymerase II preinitiation complex assembly | 2 | CAND1, PSMC3 | 0.0013772 |
GO:0045899 | Positive regulation of RNA polymerase II transcription preinitiation complex assembly | 2 | CAND1, PSMC3 | 1.20E−04 |
GO:0045898 | Regulation of RNA polymerase II transcription preinitiation complex assembly | 2 | CAND1, PSMC3 | 2.42E−04 |
GO:0045073 | Regulation of chemokine biosynthetic process | 2 | AZU1, ELANE | 3.61E−04 |
GO:0043320 | Natural killer cell degranulation | 2 | UNC13D, VAMP7 | 7.50E−05 |
GO:0043304 | Regulation of mast cell degranulation | 2 | UNC13D, VAMP7 | 0.0011382 |
GO:0042104 | Positive regulation of activated T cell proliferation | 2 | EPX, PYCARD | 7.89E−04 |
GO:0035584 | Calcium-mediated signaling using intracellular calcium source | 2 | AZU1, CCL20 | 9.21E−04 |
GO:0002693 | Positive regulation of cellular extravasation | 2 | ELANE, XG | 7.27E−04 |