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Table 1 Patient demographics and clinical characteristics

From: Eight months follow-up of corneal nerves and sensitivity after treatment with cenegermin for neurotrophic keratopathy

Nos.

Sex

Age

Eye

BCDVA (LogMAR)

Systemic disease

Eye disorder/previous ocular surgery

NK stage (Mackie)

1

M

60

OS

0.9

DM2, rheumatoid arthritis

Severe bacterial keratitis followed by PK in 2016, repeated AMTs

2

2

F

79

OS

0.5

SLE

PK for KC in 1976

2

3

M

88

OS

0.6

Recurrent HSV keratitis

3

4

F

61

OS

0.8

GVHD

Ocular GVHD, pseudomonas keratitis in 2017, PK, RGTA and AMT for PED in 2017

3

5

M

61

OS

0.4

Ocular trauma and PK in 1999, trabeculectomy in 2004

2

6

F

50

OD

0.9

Eyelash ablation for trichiasis in 1982, exposure keratopathy surgically corrected in 2002, PK in 2015, AMT in 2016

2

7

F

64

OD

0.8

PK in 1988 for KC, exposure keratopathy surgically corrected in 2016

3

8

M

65

OS

0.9

Alkali burn in 2017

3

9

F

42

OD

0.6

Recurrent HSV keratitis

2

10

F

75

OD

0.8

PK in 1991 for KC, repeated PK in 2004, lagophthalmos and exposure keratopathy surgically corrected in 2015

3

11

M

84

OS

0.4

Prostatic hyperplasia, DM2, hyperlipemia

PK in 2018 for total corneal leucoma after Corynebacterium and Staphylococcal keratitis

2

12

M

59

OS

0.5

Retinal surgery for RD with 360° endolaser retinopexy in 2018

2

13

F

88

OS

0.4

DM2, hypertension, hyperlipemia

Acoustic nerve surgery with trigeminal damage in 2010

2

14

M

62

OD

0.7

Hypertension

Alkali burn in 2015

2

15

F

55

OD

0.4

Retinal surgery for RD with 360° endolaser retinopexy in 2017

2

16

F

77

OD

0.5

Two PK performed elsewhere, PK for corneal leukoma and edema in 2018, glaucoma treated with topical therapy

2

17

F

39

OS

0.6

DM2

Retinal surgery with PRP in 2018

2

18

F

88

OS

0.6

DSAEK in 2016 for Fuchs keratopathy, recurrent HZV keratitis

2

  1. AMT, amniotic membrane transplantation; BCDVA, best corrected distance visual acuity; DM2, diabetes mellitus type 2; DSAEK, Descemet stripping automated endothelial keratoplasty; F, female; GVHD, graft versus host disease; HSV, herpes simplex virus; KC, keratoconus; M, male; OD, right eye; OS, left eye; PED, persistent epithelial defect; PK, penetrating keratoplasty; PRP, panretinal photocoagulation; RD, retinal detachment; RGTA, matrix regenerating agent; SLE, systemic lupus erythematosus