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Table 2 Calculated ARG1-D birth prevalence by country

From: Arginase 1 Deficiency: using genetic databases as a tool to establish global prevalence

Country

ARG1 carrier frequency

ARG1-D baseline birth prevalence (births/million)

ARG1-D adjusted birth prevalencea (95% CI)

Argentina

0.0017

2.85

3.06 (2.11–4.56)

Australia

0.0010

0.99

1.11 (0.87–1.55)

Austria

0.0009

0.90

1.19 (0.98–1.53)

Bahrain

0.0011

1.27

6.05 (4.78–8.23)

Belgium

0.0009

0.87

1.46 (1.23–1.84)

Brazil

0.0013

1.81

2.90 (2.19–4.02)

Canada

0.0010

1.00

1.94 (1.55–2.62)

Chile

0.0016

2.62

3.33 (2.37–4.82)

Colombia

0.0016

2.64

3.76 (2.70–5.41)

Croatia

0.0009

0.88

0.94 (0.76–1.23)

Czech Republic

0.0009

0.82

0.93 (0.76–1.25)

Denmark

0.0009

0.89

1.59 (1.35–1.97)

Finland

0.0009

0.90

0.96 (0.77–1.27)

France

0.0010

1.03

1.54 (1.24–2.04)

Germany

0.0009

0.86

1.27 (1.06–1.62)

Ireland

0.0009

0.89

1.19 (0.97–1.55)

Israel

0.0010

0.92

7.79 (6.80–9.36)

Italy

0.0010

0.91

1.21 (0.99–1.56)

Japan

0.0013

1.69

4.86 (3.46–7.43)

South Korea

0.0013

1.70

1.70 (1.02–3.15)

Kuwait

0.0011

1.21

12.97 (10.58–16.92)

Mexico

0.0016

2.55

2.85 (1.99–4.20)

Netherlands

0.0010

0.91

1.03 (0.82–1.38)

New Zealand

0.0010

0.93

1.05 (0.82–1.49)

Norway

0.0009

0.87

0.92 (0.75–1.22)

Poland

0.0009

0.88

1.17 (0.97–1.50)

Portugal

0.0010

0.91

1.81 (1.53–2.24)

Qatar

0.0012

1.35

17.48 (13.95–23.28)

Russian Federation

0.0009

0.88

1.29 (1.08–1.63)

Saudi Arabia

0.0010

0.95

14.63 (12.79–17.48)

Spain

0.0010

0.96

3.47 (2.98–4.22)

Sweden

0.0009

0.85

1.20 (1.00–1.54)

Switzerland

0.0009

0.86

1.21 (1.01–1.56)

Taiwan

0.0013

1.70

3.17 (2.15–5.14)

Turkey

0.0009

0.89

6.32 (5.59–7.39)

United Arab Emirates

0.0012

1.33

12.81 (10.09–17.44)

United Kingdom

0.0010

0.91

1.15 (0.92–1.55)

United States

0.0012

1.35

1.50 (1.09–2.20)

  1. aAdjusted for estimated consanguinity rates within each country