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Table 2 Kaplan-Maier estimates of OS by patient characteristics

From: Secondary peripheral chondrosarcoma arising in solitary osteochondroma: variables influencing prognosis and survival

Factor Level Kaplan–Maier estimates (95%CI) Log-rank
p value
HR (95%CI)
5-year 10-year
Gender F (ref) 93.8 (84.2–97.6) 87.0 (74.2–93.7) 0.583 1
  M 91.5 (84.7–95.3) 83.7 (74.8–89.6)   1.21 (0.61–2.42)
Age  < 30 (ref) 93.2 (82.9–97.4) 88.8 (76.4–94.9) 0.0262 1
  30–50 94.2 (86.5–97.5) 88.1 (78.2–93.7)   1.53 (0.65–3.62)
   > 50 86.6 (70.7–94.2) 70.4 (49.7–83.9)   3.08 (1.27–7.46)
Histological grade 1 (ref) 97.0 (91.0–99.0) 95.6 (88.6–98.4) 0.0005 1
   ≥ 2 86.9 (77.6–92.6) 73.5 (61.7–82.1)   3.74 (1.69–8.26)
Axial No (ref) 97.0 (88.3–99.2) 89.9 (82.9–94.1) 0.226 1
  Yes 90.0 (77.2–95.8) 82.3 (73.5–88.4)   1.41 (0.68–2.91)
Type of surgery Amputation 87.5 (38.7–98.1) 87.5 (38.7–98.1) 0.3616 1.08 (0.14–8.57)
  Complete resection (ref) 95.8 (87.5–98.6) 90.2 (79.2–95.5)   1
  Debulking 91.5 (78.8–96.7) 82.4 (66.1–91.4)   1.56 (0.60–4.06)
  Partial resection 91.2 (78.3–96.6) 82.2 (65.8–91.3)   2.10 (0.90–4.89)
Cartilage cap  < 3 cm (ref) 96.9 (88.1–99.2) 92.4 (80.7–97.1) 0.2524 1
   ≥ 3 cm 93.7 (83.9–97.6) 86.7 (73.6–93.6)   1.88 (0.63–5.61)
Max. tumor dimension  < 15 (ref) 93.7 (87.3–97.0) 88.8 (80.5–93.7) 0.3423 1
   ≥ 15 94.4 (79.5–98.6) 83.7 (64.9–93)   1.52 (0.64–3.61)