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Table 2 Kaplan-Maier estimates of OS by patient characteristics

From: Secondary peripheral chondrosarcoma arising in solitary osteochondroma: variables influencing prognosis and survival

Factor

Level

Kaplan–Maier estimates (95%CI)

Log-rank

p value

HR (95%CI)

5-year

10-year

Gender

F (ref)

93.8 (84.2–97.6)

87.0 (74.2–93.7)

0.583

1

 

M

91.5 (84.7–95.3)

83.7 (74.8–89.6)

 

1.21 (0.61–2.42)

Age

 < 30 (ref)

93.2 (82.9–97.4)

88.8 (76.4–94.9)

0.0262

1

 

30–50

94.2 (86.5–97.5)

88.1 (78.2–93.7)

 

1.53 (0.65–3.62)

 

 > 50

86.6 (70.7–94.2)

70.4 (49.7–83.9)

 

3.08 (1.27–7.46)

Histological grade

1 (ref)

97.0 (91.0–99.0)

95.6 (88.6–98.4)

0.0005

1

 

 ≥ 2

86.9 (77.6–92.6)

73.5 (61.7–82.1)

 

3.74 (1.69–8.26)

Axial

No (ref)

97.0 (88.3–99.2)

89.9 (82.9–94.1)

0.226

1

 

Yes

90.0 (77.2–95.8)

82.3 (73.5–88.4)

 

1.41 (0.68–2.91)

Type of surgery

Amputation

87.5 (38.7–98.1)

87.5 (38.7–98.1)

0.3616

1.08 (0.14–8.57)

 

Complete resection (ref)

95.8 (87.5–98.6)

90.2 (79.2–95.5)

 

1

 

Debulking

91.5 (78.8–96.7)

82.4 (66.1–91.4)

 

1.56 (0.60–4.06)

 

Partial resection

91.2 (78.3–96.6)

82.2 (65.8–91.3)

 

2.10 (0.90–4.89)

Cartilage cap

 < 3 cm (ref)

96.9 (88.1–99.2)

92.4 (80.7–97.1)

0.2524

1

 

 ≥ 3 cm

93.7 (83.9–97.6)

86.7 (73.6–93.6)

 

1.88 (0.63–5.61)

Max. tumor dimension

 < 15 (ref)

93.7 (87.3–97.0)

88.8 (80.5–93.7)

0.3423

1

 

 ≥ 15

94.4 (79.5–98.6)

83.7 (64.9–93)

 

1.52 (0.64–3.61)