Psychometric study of the SF-36v2 in hereditary angioedema due to C1 inhibitor deficiency (C1-INH-HAE)

Table 5 Convergent validity of the SF-36 with the HAE-QoL

Subscales HAE-QoL	SF-36
Subscales HAE-QoL	PF	RP	BP	GH	V	SF	RE	MH	PCS	MCS
Treatment difficulties	0.38	0.50	0.55	0.42	0.43	0.50	0.44	0.48	0.38	0.50
Physical functioning and health	0.40	0.60	0.60	0.52	0.46	0.52	0.43	0.50	0.40	0.60
Disease-related stigma	0.35	0.51	0.51	0.47	0.39	0.49	0.40	0.43	0.35	0.51
Emotional role and social functioning	0.42	0.59	0.56	0.51	0.50	0.59	0.45	0.50	0.42	0.59
Concern about offspring	0.17	0.30	0.36	0.33	0.28	0.30	0.27	0.30	0.17	0.30
Perceived control over illness	0.39	0.55	0.54	0.50	0.44	0.44	0.47	0.46	0.39	0.55
Mental health	0.42	0.57	0.58	0.54	0.51	0.54	0.49	0.58	0.42	0.57
Total HAE-QoL	0.42	0.64	0.64	0.58	0.53	0.59	0.52	0.57	0.45	0.64

SF-36, Short Form 36-item Health Survey Version 2.0; HAE-QoL, Hereditary angioedema quality of life; PF, physical functioning; RP, role functioning; BP, bodily pain; GH, general health perceptions; V, vitality; SF, social functioning; RE, role emotional; MH, mental health; PCS, physical component summary;
MCS, component mental summary; Pearson correlation coefficient: All correlations were statistically significant with P < .001, except for
correlation between “Perceived control over illness” from HAE-QoL and “Physical function” from SF-36 that was P = 0.004

ISSN: 1750-1172