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Table 2 Peds QoL NF1 module scores in men and women

From: A cross-sectional study of gender differences in quality of life domains in patients with neurofibromatosis type 1

Domains

Women (n = 92)

Mean ± SD

Men (n = 70)

Mean ± SD

p value

Adjusted p value§

Physical function

63.1 ± 29.9

70.6 ± 29.6

0.13

0.22

Emotion

52.5 ± 25.7

64.4 ± 24.5

0.0026

0.02

Social

62.8 ± 28.9

67.9 ± 30.1

0.30

0.39

Cognitive

54.7 ± 26.7

59.7 ± 26.0

0.24

0.37

Communication

64.1 ± 29.1

70.6 ± 29.5

0.50

0.61

Perceived physical appearance

41.4 ± 31.2

64.3 ± 30.6

< 0.0001

0.00017

Worry

49.6 ± 26.2

58.1 ± 26.6

0.05

0.10

Pain and hurt

55.2 ± 31.9

65.8 ± 32.5

0.048

0.11

Paresthesia

69.8 ± 28.5

75.2 ± 30.7

0.27

0.38

Skin irritation

73.6 ± 20.9

79.7 ± 24.9

0.11

0.20

Sensation

76.5 ± 24.2

84.9 ± 18.6

0.018

0.06

Movement and balance

79.1 ± 22.8

77.1 ± 29.0

0.65

0.73

ADLs

91.6 ± 15.0

92.2 ± 13.6

0.78

0.82

Fatigue

55.1 ± 27.1

64.9 ± 28.1

0.035

0.09

Anxiety

74.1 ± 27.6

85.9 ± 24.6

0.007

0.029

Sexual functioning

84.7 ± 20.0

83.4 ± 27.1

0.83

0.83

Total score

64.9 ± 16.5

72.9 ± 18.6

0.006

0.029

  1. §p value adjusted for multiple comparisons using the Benjamini–Hochberg method and a false discovery rate of 0.05. Bolded values are significant after adjustment