Table 1 IWQOL-Lite Summary (Age ≥ 18 Years)
Patient 1a | Patient 2a | Patient 3a | Patient 4b | Patient 5b | Patient 6b | Patient 7b | Mean (SD) | |
|---|---|---|---|---|---|---|---|---|
IWQOL-Lite total score at baseline | 50 | 43 | 70 | 74 | 77 | 52 | 56 | 60.3 (13.3) |
Change in IWQOL-Lite total score at Week 52 | 44 | 31 | 17 | 23 | 21 | – | 9 | 24.2 (12.1) |
Relevant improvement cutoffs for IWQOL-Lite total score [26]c | 12.0 | 12.0 | 12.0 | 8.3 | 8.2 | 12.0 | 12.0 | – |
Percent change in IWQOL-Lite total score at Week 52 | 88.0 | 72.1 | 24.3 | 31.1 | 27.3 | – | 16.1 | 43.1 (29.4) |
Change in domain scores at Week 52 | ||||||||
PF | 34 | 25 | 4 | 18 | 28 | – | 0 | 18.2 (13.6) |
SL | 50 | – | 69 | 0 | – | – | – | 39.7 (35.6) |
W | 63 | 38 | 19 | 62 | 19 | – | 7 | 34.7 (23.7) |
PD | 40 | 30 | 0 | 10 | 25 | – | 20 | 20.83 (14.3) |
SE | 47 | 39 | 18 | 29 | 7 | – | 14 | 25.7 (15.4) |
Body weight, percent change | − 34.8 | − 25.8 | − 27.7 | − 21.0 | − 15.6 | – | − 2.3 | − 21.2 (11.3) |
Most hunger, percent change | − 14.3 | − 5.8 | − 72.2 | − 64.3 | − 66.7 | – | − 37.5 | − 43.5 (28.7) |