From: Do clinical guidelines facilitate or impede drivers of treatment in Fabry disease?
 | Angiokeratoma | Organ biopsy | Non-pain GI symptoms | Sweating abnormalities or heat/exercise intolerance | Febrile crises | Patient-reported progression of symptoms/signs |
---|---|---|---|---|---|---|
PREDICT-FDa [11] |  +  |  +  |  +  |  +  |  +  |  +  |
EFWGb [1] | Diagnostic sign | – | Aged < 16 years All, IIA Aged ≥ 16 years All, IIB |  |  |  |
Australia [24] | – | – | – | – | – | – |
Canada [21] | Diagnostic sign | Diagnostic/prognostic | Allc | – | – | – |
Catalonia (Spain) | – | – | – | – | – | – |
Diagnostic sign | – | – | – | – | – | |
Portugal [22] | – | – | All, recurrent diarrhea attributable to FD | All | – | – |
Slovenia (FCGHSG) | Diagnostic sign | Confirmatory skin biopsy if needed in asymptomatic boys with classical disease | Postprandial diarrheae | Alle | – | – |
Switzerlandf | – | – | F | – | – | – |
UKg [26] | – | – | – | – | – | – |