Table 1 Distribution of genetic variants in different group
CHD group | n | Chromosomal abnormalities | ||
|---|---|---|---|---|
Aneuploidies | Clinical significant CNVs | Total | ||
Isolated CHD | 134 | 10 (7.5%) | 18 (13.4%) | 28 (20.9%) |
Non-isolated CHD | 66 | 13 (19.7%)* | 8 (12.1%) | 21 (31.8%) |
CHD plus structural anomalies | 28 | 3(10.7%) | 5(17.9%) | 8(28.6%) |
CHD plus soft marker | 22 | 5(22.7%)* | 1(4.5%) | 6(27.3%) |
CHD plus structural anomalies & soft marker | 16 | 5(31.3%)* | 2(12.5%) | 7(43.8%) |
Simple CHD | 178 | 20(11.2%) | 22(12.4%) | 42(23.6%) |
Complex CHD | 22 | 3(13.6%) | 4(18.2%) | 7(31.8%) |