Orphanet Journal of Rare Diseases

Table 4 Psychometric validation: correlations between the ctGD1-PROM items and SF-36 PCS and MCS scores

From: Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials

Items	Correlation with PCS			Correlation with MCS
Items	Coefficient	(p < 0.05)	(p < 0.1)	Coefficient	(p < 0.05)	(p < 0.1)
GD Education/job	0.739	✓	✓	0.792	✓	✓
GD Friends	0.594	✓	✓	0.722	✓	✓
GD Intimate	0.633	✓	✓	0.702	✓	✓
GD Hobbies leisure	0.684	✓	✓	0.724	✓	✓
GD Emotional burden	0.616	✓	✓	0.742	✓	✓
GD General-specific med	0.205	x	x	0.383	✓	✓
GD Concerns Gaucher	0.139	x	x	0.023	x	x
GD Current med. concerns	0.172	x	x	0.358	✓	✓
GD Dependent	0.715	✓	✓	0.274	x	✓
GD Abdomen	0.478	✓	✓	0.415	✓	✓
GD Fatigued	0.680	✓	✓	0.609	✓	✓
GD Physical weakness	0.750	✓	✓	0.615	✓	✓
GD Bone pain	0.787	✓	✓	0.594	✓	✓
GD Depressed	0.514	✓	✓	0.808	✓	✓
GD Worried	0.566	✓	✓	0.819	✓	✓
GD Future	0.567	✓	✓	0.647	✓	✓
GD Satisfied	0.656	✓	✓	0.691	✓	✓

GD Gaucher disease, MCS mental component score, PCS physical component score, SF-36 36-item Short Form Health Survey

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ISSN: 1750-1172

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