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Table 4 Psychometric validation: correlations between the ctGD1-PROM items and SF-36 PCS and MCS scores

From: Development and validation of Gaucher disease type 1 (GD1)-specific patient-reported outcome measures (PROMs) for clinical monitoring and for clinical trials

Items Correlation with PCS Correlation with MCS
Coefficient (p < 0.05) (p < 0.1) Coefficient (p < 0.05) (p < 0.1)
GD Education/job 0.739 0.792
GD Friends 0.594 0.722
GD Intimate 0.633 0.702
GD Hobbies leisure 0.684 0.724
GD Emotional burden 0.616 0.742
GD General-specific med 0.205 x x 0.383
GD Concerns Gaucher 0.139 x x 0.023 x x
GD Current med. concerns 0.172 x x 0.358
GD Dependent 0.715 0.274 x
GD Abdomen 0.478 0.415
GD Fatigued 0.680 0.609
GD Physical weakness 0.750 0.615
GD Bone pain 0.787 0.594
GD Depressed 0.514 0.808
GD Worried 0.566 0.819
GD Future 0.567 0.647
GD Satisfied 0.656 0.691
  1. GD Gaucher disease, MCS mental component score, PCS physical component score, SF-36 36-item Short Form Health Survey