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Fig. 1 | Orphanet Journal of Rare Diseases

Fig. 1

From: Small fiber neuropathy for assessment of disease severity in amyotrophic lateral sclerosis: corneal confocal microscopy findings

Fig. 1

Representative CCM images of the inferior whorl area and peripheral area in control and ALS. In a control participant, the intact whorl-like pattern of the subbasal nerve plexus in the inferior whorl area (a) and the parallel nerve in the peripheral area (b) could be detected. In a patient with ALS, an impaired nerve pattern with increased dendritic cells in the inferior whorl area (c) and in the peripheral area (d) could be detected. CCM, corneal confocal microscopy; ALS, amyotrophic lateral sclerosis

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