From: Osteogenesis Imperfecta: characterization of fractures during pregnancy and post-partum
Fractures N = 12 | No fracture N = 38 | p | |
---|---|---|---|
Smoking (%) | 2/12 (16.7) | 10/29 (34.5) | 0.45 |
BMI < 19 kg/m2 (%) | 2/10 (20) | 2/29 (6.9) | 0.27 |
Corticosteroids (%) | 0 | 1/29 (3.4) | 1 |
Osteoporosis inducing disease | |||
Spondyloarthritis | 1/12 (8.3) | 0 | 0.2 |
Inflammatory bowel disease | 1/12 (8.3) | 0 | 0.2 |
Anorexia | 1/12 (8.3) | 1/29 (3.4) | 0.50 |
Rheumatoid arthritis | 0 | 1/29 (3.4) | 1.0 |
Immobilization | 3/10 (30.0) | 3/29 (10.3) | 0.16 |
25OHD < 30 ng/ml (%) | 2/10 (20.0) | 13/27 (48.1) | 0.15 |
Low calcium intake (%) | 1/12 (8.3) | 1/29 (3.4) | 0.50 |
Spine BMD (Z-score) | − 2.93 ± 1.57 | − 1.48 ± 1.67 | 0.03 |
Femoral neck BMD (Z-score) | − 2.25 ± 0.90 | − 0.7 ± 1.19 | 0.09 |
Total hip BMD (Z-score) | − 2.05 ± 0.74 | − 0.53 ± 1.36 | 0.04 |
At least 1 risk factor, % | 9/11 (81.8) | 17/29 (58.6) | 0.27 |