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Table 1 Characteristics of the female OI cohort with pregnancies

From: Osteogenesis Imperfecta: characterization of fractures during pregnancy and post-partum

OI female cohort

Total OI cohort

50 patients

Type I, N (%)

28/36 (77.8)

Genetically confirmed (%)

30/50 (60.0)

Number of fractures before pregnancy < 5, N (%)

15/49 (30.6)

Number of fractures before pregnancy 5–10, N (%)

9/49 (18.4)

Number of fractures before pregnancy 11–50, N (%)

22/49 (44.9)

Number of fractures before pregnancy > 50, N (%)

4/49 (8.2)

Age at OI diagnosis (years, mean ± SD)

13.7 ± 14.8

Blue sclera, N (%)

32/38 (84.2)

Deafness, N (%)

12/40 (30.0)

Joint Hyperlaxity, N (%)

20/38 (52.6)

Scoliosis or kyphosis, N (%)

20/39 (51.3)

Spine surgery or telescopic rods, N (%)

10/48 (21.3)

Wheelchair or walking stick, N (%)

8/46 (18.6)

Time between last fracture and pregnancy (years, mean ± SD)

10.2 ± 7.7

Bisphosphonates before pregnancy, N (%)

10/50 (20.0)

Time since bisphosphonates (years, mean ± SD)

8.1 ± 4.9

Height (cm, mean ± SD)

153.8 ± 12.7

Weight (kg, mean ± SD)

56.8 ± 12.8

BMI (kg/m2, mean ± SD)

24.1 ± 4.9

  1. Bold refers to %