Fig. 2

Lymphocyte subpopulations and CXCR4-CD26 surface expressions. In 36 HHT patients (black bar or dots) and 18 healthy control subjects (grey bar or dots) matched by age and sex: a absolute counts of T, B and NK lymphocytes, b absolute counts of T-helper lymphocytes (total, naive, memory and activated), c absolute counts of T-cytotoxic lymphocytes (total, naive, memory and activated), d CXCR4 expression on T-helper, T-cytotoxic and NK lymphocytes, e CD26 expression on T-helper, T-cytotoxic and NK lymphocytes, f ratio of CXCR4/CD26 expressions on T-helper, T-cytotoxic and NK lymphocytes, g CXCR4 expression on naive, memory and activated T-helper lymphocytes, h CD26 expression on naive, memory and activated T-helper lymphocytes, i ratio of CXCR4/CD26 expressions on naive, memory and activated T-helper lymphocytes, j correlation between absolute counts of T-helper lymphocytes and their expression of CXCR4 in the HHT group, k correlation between absolute counts of T-helper lymphocytes and their expression of CD26 in the HHT group, l correlation between CXCR4 and CD26 surface expression on T-helper lymphocytes in the HHT group, m correlation between absolute counts of T-helper lymphocytes and their expression of CXCR4 in the control group, n correlation between absolute counts of T-helper lymphocytes and their expression of CD26 in the control group, o correlation between CXCR4 and CD26 surface expression on T-helper lymphocytes in the control group. MFI: mean fluorescence intensity. Results are presented in bar charts with median and interquartile ranges (for comparisons) or individual values with Spearman r coefficients (for correlations). Comparisons between groups were performed using the Mann–Whitney U-test. Correlations between variables were performed using the Spearman’s rank test. P-values are shown