Table 3 Cases of primary cervical GTN in a comprehensive literature review
Case | Reference | Age | Primary diagnosis | Primary treatment | β-hCG | Complementary surgery | Chemotherapy | Follow-up (month) |
|---|---|---|---|---|---|---|---|---|
1 | Fu et al. [2] | 46 | Abortion | Curettage | 20,000 | Hysterectomy | Yes | CR (17) |
2 | Â | 21 | GTN | Chemotherapy | 5344 | Hysterectomy | Yes | CR (16) |
3 | Â | 35 | Abortion | Curettage | 4000 | Hysterectomy | Yes | CR (14) |
4 | Â | 30 | Abortion | Curettage | 2764 | Hysterectomy | Yes | CR (6) |
5 | Baykal et al. [3] | 54 | Cervical cancer | Cervical biopsy*, RH + BSO + BLN | 45,000 | No | Yes | NA |
6 | Ben et al. [4] | 35 | Cervical myoma | Curettage | NA | Hysterectomy | Yes | NA |
7 | Sorbi et al. [5] | 30 | CSP | Hysterectomy | 60,000 | No | Yes | NA |
8 | Lee et al. [6] | 29 | Cervical pregnancy | MTX + Hysterectomy | 180,580 | No | Yes | NA |
9 | Mitrovic et al. [7] | 35 | NA | Hysterectomy | 13 | No | No | NA |
10 | Herts et al. [8] | 47 | Cervical pregnancy | Hysterectomy | 109,870 | No | Yes | NA |
11 | Kairi-Vassilatou et al. [9] | 43 | Ectopic pregnancy | MTX + Curettage | 7485 | Hysterectomy | Yes | NA |
12 | Ben-Chetrit et al. [10] | 33 | Cervical cancer | Cervical biopsy*, Cervical conization | 32 | No | Yes | CR (12) |
13 | Frati et al. [11] | 32 | Cervical cancer | Cervical biopsy | 30,750 | No | Yes | NA |
14 | Yahata et al. [12] | 38 | Cervical polyp | Cervical biopsy | 12,800 | Hysterectomy | Yes | CR (14) |
15 | Chandacham et al. [13] | 33 | Cervical cancer | Cervical biopsy | 45,724 | No | Yes | CR (33) |
16 | Wang et al. [14] | 27 | NA | Cervical biopsy | 1900 | Hysterectomy | Yes | CR (8) |
17 | Tsai et al. [15] | 46 | GTN | Hysterectomy | 162,550 | No | Yes | NA |
18 | Â | 43 | Cervical cancer | Hysterectomy | NA | No | Yes | NA |
19 | Â | 29 | GTN | Hysterectomy | NA | No | Yes | NA |
20 | Park et al. [16] | 31 | NA | Cesarean section + tumor resection | NA | Hysterectomy | Yes | NA |
21 | Tsukamoto et al. [17] | 42 | Cervical cancer | Cervical biopsy* | 8000 | Hysterectomy | Yes | NA |
22 | Tripathi et al. [18] | 28 | NA | Curettage | 54,000 | Hysterectomy | Yes | CR (10) |
23 | Karaman et al. [19] | 36 | Ectopic pregnancy | MTX + Cervical biopsy | 5374 | No | Yes | NA |
24 | Phippen et al. [20] | 40 | Cervical cancer | Cervical biopsy* Cervical conization | 20 | Hysterectomy | No | NA |
25 | Wang et al. [21] | 36 | Cervical pregnancy | Cervical pregnancy | 149,100 | No | Yes | NA |
26 | Roopnarinesingh et al. [22] | 25 | Ectopic pregnancy | Laparoscopic exploration + cervical biopsy +curettage | 4580 | No | Yes | Relapse (6) |
27 | Zwischenberger et al. [23] | 38 | Cervical cancer | Cervical biopsy | 13 | Hysterectomy | No | NA |