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Table 2 Metabolic control

From: Preventing maternal phenylketonuria (PKU) syndrome: important factors to achieve good metabolic control throughout pregnancy

 

Group "ideal"

Group "suboptimal"

p

n = 23

n = 51

(Mann–Whitney U)

Blood Phe concentration during pregnancy (µmol/l)

   

Range of all measurements

6–762

8–1195

 

Mean of mean values (SD)

158 (35)

292 (160)

 

Median of mean values (IQR)

154 (123–188)

245 (202–292)

 < 0.001

Range of mean values

101–225

115–882

 

Phe > 360 µmol/l: n (%)

   

Mean (SD)

1.3 (2)

26 (25)

 

Median (IQR)

0 (0–3)

34 (28–40)

 < 0.001

range

0–5

6–100

 

Clinical signs of maternal PKU syndrom: n* (%)

0

14 (27)

n.a

Heart defect

0

1 (2)

 

Microcephaly

0

4 (8)

 

Microsomia

0

2 (4)

 

Behavior abnormalitie

0

7 (14)

 

Developmental delay

0

6 (12)

 

Special school

0

6 (12)

 
  1. *7 children suffering from more than one clinical sign suspicious of maternal PKU syndrome