Group "ideal" | Group "suboptimal" | p | |
---|---|---|---|
n = 23 | n = 51 | (Mann–Whitney U) | |
Blood Phe concentration during pregnancy (µmol/l) | |||
Range of all measurements | 6–762 | 8–1195 | |
Mean of mean values (SD) | 158 (35) | 292 (160) | |
Median of mean values (IQR) | 154 (123–188) | 245 (202–292) | < 0.001 |
Range of mean values | 101–225 | 115–882 | |
Phe > 360 µmol/l: n (%) | |||
Mean (SD) | 1.3 (2) | 26 (25) | |
Median (IQR) | 0 (0–3) | 34 (28–40) | < 0.001 |
range | 0–5 | 6–100 | |
Clinical signs of maternal PKU syndrom: n* (%) | 0 | 14 (27) | n.a |
Heart defect | 0 | 1 (2) | |
Microcephaly | 0 | 4 (8) | |
Microsomia | 0 | 2 (4) | |
Behavior abnormalitie | 0 | 7 (14) | |
Developmental delay | 0 | 6 (12) | |
Special school | 0 | 6 (12) |