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Table 1 Patient characteristics

From: Preventing maternal phenylketonuria (PKU) syndrome: important factors to achieve good metabolic control throughout pregnancy

 

Group "ideal"

Group "suboptimal"

p (Mann–Whitney-U)

n = 23

n = 51

Patients: n (%)

   

Planned pregnancies

22 (96)

40 (78)

1

Unplanned pregnancies

1 (4)

11 (22)

1

Pregnancies: n (%)

   

First

18 (78)

31 (61)

1

Second

5 (22)

16 (31)

1

Third

0 (0)

4 (8)

 

Phe tolerance before pregnancy (mg/day)

   

Mean (SD)

587 (235)

572 (264)

0.798

Median (IQR)

560 (400–787)

500 (362–800)

 

Range

250–950

300–1200

 

Phe-tolerance known before pregnancy: n (%)

   

Known

12 (52)

28 (55)

1

Unknown

11 (48)

23 (45)

1

Blood Phe-analyses during pregnancy (n)

   

Mean (SD)

38 (14)

33 (12)

 

Median (IQR)

35 (29–42)

34 (28–40)

0.345

Range

17–79

5–66

 

Diet implementation: n (%)

   

Calculation of all foods

2 (9)

10 (20)

0.320

Calculation of all foods except fruit, vegetables and low protein foods

0 (0)

1 (2)

1

No consumption of protein-rich foods and estimation of Phe-intake

7 (30)

14 (27)

1

Consumption of protein-rich foods and estimation of Phe-intake

9 (39)

12 (24)

0.265

None

5 (22)

14 (27)

0.776

Feeling about diet: n (%)

   

Very hard

2 (9)

5 (10)

1

Hard

4 (17)

13 (25)

0.558

Easy

14 (57)

22 (43)

0.211

Very easy

4 (17)

10 (20)

1

Age of mothers at beginning of pregnancy (years)

   

Mean (SD)

29.5 (4,3)

28.90

 

Median (IQR)

29 (26–33)

29 (26–32)

0.258

Range

21–38

19–39

 

Mothers highest achieved degree of school education: n (%)

   

Primary school

0 (0)

0 (0)

1

School for mentally handicapped children

0 (0)

2 (4)

0.566

9th grade

0 (0)

6 (12)

0.168

10th grade

10 (43)

29 (57)

0.323

12th grade

13 (57)

14 (27)

0.013*