Table 8 NPC symptoms participants asked to rank in survey
From: Impacts and Burden of Niemann pick Type-C: a patient and caregiver perspective
NPCCSS Domain | Symptom Asked to Rank in Survey |
|---|---|
Ambulation | Unsteadiness or clumsiness when walking about from place to place (ataxia) |
Fine Motor | Difficulty with coordinating hand movements (dystonia) |
Speech | Slurred or irregular speech (dysarthria) |
Swallow | Difficulty swallowing (dysphagia) |
Eye Movement | Difficulty moving one’s eyes up and down (vertical supranuclear gaze palsy) |
Seizures | Seizures |
Memory | Memory problems |
Hearing | Hearing difficulties |
Cognition | Learning difficulties or problems with cognitive abilities like following instructions, making decisions, or focusing attention (cognitive dysfunction or dementia) |
Other | Participant could write up to three other symptoms to rank as most important |