From: Clinics and genetic background of hereditary gingival fibromatosis
Chromosomal region/gene locus | Affected# or candidate## gene | Gene/locus MIM number | Disease type | Phenotype MIM number | Inheritance | References |
---|---|---|---|---|---|---|
2p21-p22 (D2S1788, D2S441) GINGF, GINGF1, GGF1 | SOS-1# | 182530 | Hereditary gingival fibromatosis type 1 (HGF1) | 135300 | AD | |
2p16-p13 (D2S1788, D2S2298) GINGF | – | – | Hereditary gingival fibromatosis type 1 (HGF1) | 135300 | AD, AR | |
5q13-q22 (D5S1491, D5S1453) GINGF2, GGF2 | CAMK4## | 114080 | Hereditary gingival fibromatosis type 2 (HGF2) | 605544 | AD | |
2p23.3-p22.3 (D2S2221, D2S1788) GINGF3, GGF3 | – | – | Hereditary gingival fibromatosis type 3 (HGF3) | 609955 | AD | |
11p15 (D11S1984- D11S1338) GINGF4, GGF4 | – | – | Hereditary gingival fibromatosis type 4 (HGF4) | 611010 | MI | |
4q12 GINGF5, GGF5 | REST# | 600571 | Hereditary gingival fibromatosis type 5 (HGF5) | 617626 | AD |