Fig. 1

Phenotypic heterogeneity of hereditary gingival fibromatosis. A. the photography shows the gingiva from a 10-year-old Caucasian male patient diagnosed with HGF. Both mother of the patient and her sister are also affected. The surface of the gingiva is almost homogeneous, smooth and with a normal stippling of the attached gingiva. An unusually wide zone of the keratinized gingiva is equally distributed along teeth in both dental arches in the maxilla and in the mandible. The margin of gingiva obscures half of the crowns’ height, which makes teeth appearing not completely erupted; B.  a 15-year-old Caucasian female diagnosed with asymmetric gingival overgrowth of hereditary origin in the maxilla and in the mandible. Hypertrophy of gingiva caused spacing between teeth. It also makes clinical crowns appearing to be shorter than their anatomical length. Gingiva around some teeth looks almost normal while in other locations it presents a significant amount of keratinized tissue, which covers the teeth surface. The surface of the gingiva is heterogeneous at different sites of oral cavity. Some areas are smooth with a normal stippling of the gingiva, whereas other resemble multiple verrucous lesions. Some interdental papillae are overgrown, inflamed, and bleed easily during tooth brushing