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Table 2 Age at diagnosis, by sex, in patients with isolated growth hormone deficiency, ectopic neurohypophysis, isolated congenital hypogonadotropic hypogonadism and gonadal dysgenesis

From: Age at diagnosis in patients with chronic congenital endocrine conditions: a regional cohort study from a reference center for rare diseases

 

Female

Median age (interquartile range), in years

Male

Median age (interquartile range), in years

p

Isolated growth hormone deficiency

8.83

(4.33–11.25)

n = 614

8.17

(4.50–11.42)

n = 979

0.073

Ectopic posterior pituitary syndrome

2.50

(0.83–4.83)

n = 141

4.00

(0.50–8.27)

n = 223

0.001

Isolated congenital hypogonadotropic hypogonadism

18.50

(16.00–26.00)

n = 299

16.00

(11.88–23.00)

n = 462

< 0.001

Gonadal dysgenesis 46,XY/45,X

0.00

(0.00–0.08)

n = 19

0.00

(0.00–11.6)

n = 49

0.026

  1. Values are expressed as median (interquartile range), or number