Table 1 Age at diagnosis for seven congenital endocrine diseases, by age category
Number of patients (Female%) | Missing data N (%) | Median age at diagnosis (years) | Patients diagnosed < 5 years old | Patients diagnosed [5–11) years old | Patients diagnosed [11–18) years old | Patients diagnosed ≥18 years old | |
|---|---|---|---|---|---|---|---|
Idiopathic isolated growth hormone deficiency | 1593 (38.5%) | 97 (6.1%) | 8.42 (4.42-11.33) | 418 (26.2%) | 637 (40%) | 435 (27.3%) | 6 (0.4%) |
Ectopic posterior pituitary syndrome | 364 (38.7%) | 0 | 3.42 (0.50-7.50) | 230 (63.2%) | 90 (24.7%) | 41 (11.3%) | 3 (0.8%) |
Isolated congenital hypogonadotropic hypogonadism | 761 (39.3%) | 48 (6.3%) | 17.42 (14.00-25.00) | 105 (13.8%) | 21 (2.8%) | 237 (31.1%) | 350 (46%) |
Turner syndrome* | 1478 (100%) | 38 (2.6%) | 9.00** (0.67-13.69) | 478 (32.3%) | 397 (26.9%) | 393 (26.6%) | 172 (11.6%) |
McCune-Albright Syndrome | 38 (94.7%) | 1 (2.6%) | 4.67 (2.50-6.58) | 23 (60.5%) | 12 (31.6%) | 2 (5.3%) | ND |
Complete androgen insensitivity syndrome | 77 (100%) | 7 (9.1%) | 9.25 (0.21-16.00) | 33 (42.8%) | 3 (3.9%) | 17 (22.1%) | 17 (22.1%) |
Gonadal dysgenesis 46,XY/45,X | 68 (27.9%) | 3 (4.4%) | 0.00 (0.00-9.25) | 45 (66.2%) | 6 (8.8%) | 8 (11.8%) | 6 (8.8%) |