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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Alterations in brain morphology by MRI in adults with neurofibromatosis 1

Fig. 4

Correlation matrix of principal components of 2D brain morphological measurements with 3D brain volumetric measurements of the corpus callosum (A) and brainstem (B) in adults with NF1.The color scale represents the degree of correlation from strongly negative (− 1, red) to strongly positive (1, blue). The size of the circles also indicates the strength of the correlation, with values closer to − 1 or 1 larger than those that are closer to 0. Asterisks indicate FDR-adjusted statistical significance. p < 0.05 = *, p < 0.01 = **, p < 0.001 = ***. Abbreviations: eTIV = total brain volume, GM = grey matter volume, WM = white matter volume, WMCC = corpus callosum white matter volume, WMBS = brainstem white matter volume, and PC = principal component

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