Fig. 3
From: Alterations in brain morphology by MRI in adults with neurofibromatosis 1
Location of brainstem measurements shown on representative sagittal (A), axial (B), (C), and (D) images, and average measurements (E) for adults with NF1 and unaffected control participants. A–D Representative MRI images showing T1-weighted midline sagittal and T2-weighted axial views of a 25-year-old male with NF1. E Average brainstem measurements. The labeled lines in A show position of the midbrain (B), the pons and the middle cerebellar peduncle (C), and the medulla oblongata (D). Coloured lines in B–D show where structures indicated by the same colour in E are measured. Error bars indicating one standard deviation and asterisks indicating FDR-adjusted statistical significance are shown in E. p < 0.001 = ***. Abbreviations used in the figure: L = left, R = right, AP = anterior to posterior length, and MCP = middle cerebellar peduncle