Fig. 2From: Prevalence of low alkaline phosphatase activity in laboratory assessment: Is hypophosphatasia an underdiagnosed disease?Overview of typical HPP symptoms and their localization. Hypophosphatasia is a metabolic multisystemic disease with various organ systems involved. In addition to musculoskeletal symptoms such as stress fractures, joint and muscle pain, neurological symptoms and gastrointestinal complaints may also occurBack to article page