High rate of autonomic neuropathy in Cornelia de Lange Syndrome

Table 4 SGD by decades of life

	Controls	N	CdLS NIPBL	N	p^a
Mean SGD (g/cm²) ± SD	217.60 ± 30.61	50	178.03 ± 72.53	27	0.001
Mean SGD (g/cm²) ± SD by decades of life	Controls	N	CdLS NIPBL	N	p^a
≤ 10 years	236.76 ± 34.81	13	226.00 ± 86.60	10	0.686
11–20 years	217.18 ± 29.99	11	159.09 ± 45.35	11	0.002
21–30 years	206.40 ± 22.9	10	139.00 ± 59.90	3	0.010
31–40 years	215.28 ± 32.40	8	143.00 ± 22.62	2	0.013
41–50 years	202.50 ± 22.16	8	94.0	1	0.002

Values for sweat gland density in CdLS individuals with variants in NIPBL and controls by groups of age
^aIndependent samples t test. There are statistically significant differences (p < 0.05) in the SGD global mean (control group compared to the global NIPBL group) and by decades of life, in all the decades except in the first one

ISSN: 1750-1172