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Fig. 3 | Orphanet Journal of Rare Diseases

Fig. 3

From: Reduced risk of recurrent pneumothorax for sirolimus therapy after surgical pleural covering of entire lung in lymphangioleiomyomatosis

Fig. 3

Kaplan–Meier curves of recurrence-free survival (RFS) after surgical pleural covering including total pleural covering and modified total pleural covering for pneumothorax in lymphangioleiomyomatosis. A Kaplan–Meier curve of RFS in total surgeries (n = 24). Five years RFS is 82.9%. B Kaplan–Meier curves of RFS in the sirolimus (n = 16) and the non-sirolimus groups (n = 8). The RFS in the sirolimus group is significantly better than that in the non-sirolimus group (p = 0.001, log-rank test revealed). C Kaplan–Meier curves of RFS in the high serum vascular endothelial growth factors D (VEGF-D) group (> 938 pg/mL, n = 12) and in the low serum VEGF-D group (≤ 938 pg/mL, n = 12). There are no significant differences between the high serum VEGF-D level and the low VEGF-D group (p = 0.31)

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Orphanet Journal of Rare Diseases

ISSN: 1750-1172