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Table 1 Seven natural TAND clusters identified in this study

From: Multivariate data analysis identifies natural clusters of Tuberous Sclerosis Complex Associated Neuropsychiatric Disorders (TAND)

Natural TAND cluster No. of items TAND checklist items Internal consistency (alpha)
Scholastic 4 Reading
Writing
Spelling
Mathematics
0.97a
Neuropsychological 7 Memory
Disorientation
Attention difficulties (behaviour)
Neuropsychological attention deficits
Visuo-spatial
Dual-tasking
Executive skills
0.87a
Autism Spectrum Disorder-Like 6 Inflexible
Unusual language
Repetitive behaviour
Poor eye contact
Peer difficulties
Delayed language
0.79a
Dysregulated behaviour 3 Aggressive outbursts
Temper tantrums
Self-injury
0.73a
Overactive/Impulsive 3 Overactive
Impulsive
Restless
0.70a
Mood/Anxiety 4 Mood swings
Anxiety
Depressed mood
Extreme shyness
0.69
Eat/Sleep 2 Eating difficulties
Sleep difficulties
0.48
  1. The table shows the clusters with items contained and internal consistency of each cluster
  2. aCronbach alpha ≥ 0.7 indicates good internal consistency