Fig. 4

Effects of low-dose calcipotriol treatment on wound microbiome. a Scatter plot showing species richness on intact skin compared to wounds. Each dot represents an individual wound at baseline (day 0). Statistical analysis; Mann Whitney test, ***P = 0.0001. b Relative abundance of staphylococcus species in all wounds and on intact skin at baseline (day 0). c Microbial species richness of wounds at baseline, after 14 and 28 day-treatment with low-dose calcipotriol or placebo. Data are presented as mean of two wounds of individual patients. d Species richness in open vs completely closed wounds after 14 and 28 day- treatment with low-dose calcipotriol or placebo