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Fig. 2 | Orphanet Journal of Rare Diseases

Fig. 2

From: Impact of low-dose calcipotriol ointment on wound healing, pruritus and pain in patients with dystrophic epidermolysis bullosa: A randomized, double-blind, placebo-controlled trial

Fig. 2

Impact of low-dose calcipotriol treatment on wound healing. a Size of wound area (%) representing mean with 95% confidence intervals (CIs) at baseline (day 0), 14 and 28 days of treatment with low-dose calcipotriol or placebo. Statistical analysis; generalized estimation-equation model based on gamma distribution, * P = 0.006. b Heat plot showing numbers of wounds with 0–10%, 10–20%, 25–50%, 50–100% or > 100% wound area compared to baseline after treatment with low-dose calcipotriol or placebo at 14 and 28 days. c Clinical pictures of wounds of a patient responding well to low-dose calcipotriol (0.05 µg/g) treatment at baseline, 14 and 28 days of treatment with low-dose calcipotriol or placebo

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