Characteristics | All (n = 31) | Premenopausal (n = 23) | Postmenopausal (n = 8) | P value |
---|---|---|---|---|
Age | 34 (14–66) | 30 (14–52) | 60 (56–66) | |
Presenting symptom | ||||
Hirsutism | 28 (90.3) | 20 (87) | 8 (100) | 0.550 |
Alopecia | 6 (19.4) | 3 (13) | 3 (37.5) | 0.161 |
Acne | 6 (19.4) | 5 (21.7) | 1 (12.5) | 1.000 |
Deepened voice | 11 (35.5) | 7 (30.4) | 4 (50) | 0.405 |
Clitoromegaly | 15 (48.4) | 12 (52.2) | 3 (37.5) | 0.685 |
Symptom duration (months) (range) | 36 (6–168) | 36 (12–168) | 27 (6–132) | 0.317 |
Testosterone level (ng/ml) (range) | 3.6 (1.2–16.2) | 3.6 (1.2–14.4) | 3.7 (1.9–16.4) | 0.74 |
Tumor diameter (cm) (range) | 3.1 (0.7–11.9) | 4.5 (0.7–11.9) | 1.8 (1.3–4.8) | 0.018* |
Histotype | ||||
Sertoli-Leydig cell tumors | 9 (29.0) | 9 (39.1) | – | 0.041* |
Leydig cell tumors | 9 (29.0) | 3 (13) | 6 (75) | 0.010* |
Steroid cell tumors | 7 (22.6) | 6 (26.1) | 1 (12.5) | 0.015* |
Granulosa cell tumors | 4 (12.9) | 3 (13) | 1 (12.5) | 1.000 |
Sclerosing stromal tumor | 1 (3.2) | 1 (4.3) | – | |
Sex cord tumor with annular tubules | 1 (3.2) | 1 (4.3) | – |