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Table 1 Clinicopathological features of 31 patients with VOTs

From: Clinical and ultrasound characteristics of virilizing ovarian tumors in pre- and postmenopausal patients: a single tertiary center experience

Characteristics

All

(n = 31)

Premenopausal

(n = 23)

Postmenopausal

(n = 8)

P value

Age

34 (14–66)

30 (14–52)

60 (56–66)

 

Presenting symptom

 Hirsutism

28 (90.3)

20 (87)

8 (100)

0.550

 Alopecia

6 (19.4)

3 (13)

3 (37.5)

0.161

 Acne

6 (19.4)

5 (21.7)

1 (12.5)

1.000

 Deepened voice

11 (35.5)

7 (30.4)

4 (50)

0.405

 Clitoromegaly

15 (48.4)

12 (52.2)

3 (37.5)

0.685

Symptom duration (months) (range)

36 (6–168)

36 (12–168)

27 (6–132)

0.317

Testosterone level (ng/ml) (range)

3.6 (1.2–16.2)

3.6 (1.2–14.4)

3.7 (1.9–16.4)

0.74

Tumor diameter (cm) (range)

3.1 (0.7–11.9)

4.5 (0.7–11.9)

1.8 (1.3–4.8)

0.018*

Histotype

 Sertoli-Leydig cell tumors

9 (29.0)

9 (39.1)

0.041*

 Leydig cell tumors

9 (29.0)

3 (13)

6 (75)

0.010*

 Steroid cell tumors

7 (22.6)

6 (26.1)

1 (12.5)

0.015*

 Granulosa cell tumors

4 (12.9)

3 (13)

1 (12.5)

1.000

 Sclerosing stromal tumor

1 (3.2)

1 (4.3)

 

 Sex cord tumor with annular tubules

1 (3.2)

1 (4.3)

 
  1. Data are given as n or n (%)
  2. Asterisks (*) indicate statistically significant differences between the two groups (*P < 0.05 and **P < 0.01)