Table 3 Factors for prediction of gastrointestinal ulcer in BD patients
Variable | BD patients without gastrointestinal ulcer | BD patients with gatrointestinal ulcer | Univariate analysis, P value | Multivariate analysis, P value |
|---|---|---|---|---|
Sex(F/M) | 477:482 | 122:151 | 0.080 | |
Age at diagnosis | 38.91 ± 13.53 | 39.33 ± 14.62 | 0.660 | |
Smoking history | 87:872 | 28:245 | 0.312 | |
Archenteric symptoms | 913:46 | 168:105 | < 0.001 | < 0.001 OR 0.070 |
Oral ulcer n (%) | 949 (98.96) | 269 (98.53) | 0.377 | |
Genital ulcer (%) | 659 (68.72) | 179 (65.56) | 0.181 | |
Skin lesion (%) | 471 (49.11) | 117 (42.85) | 0.039 | n.s |
Ocular (%) | 164 (17.10) | 16 (5.86) | < 0.001 | 0.011 OR 3.738 |
Hematological (MDS/+8) (%) | 9 (0.94) | 12 (4.40) | < 0.001 | n.s |
Cardiac valvular lesions (%) | 25 (2.61) | 2 (0.73) | 0.041 | n.s |
Venous thrombosis (%) | 24 (2.50) | 9 (3.30) | 0.297 | |
Aneurysms (%) | 32 (3.34) | 7 (2.56) | 0.338 | |
Fever (%) | 9 (0.94) | 32 (11.72) | < 0.001 | 0.047 OR 0.115 |
ESR (mm/h) | 12 (6 ~ 25) | 19 (8 ~ 40) | 0.001 | n.s |
CRP (mg/L) | 6.5 (1.86 ~ 10) | 9.7 (3.75 ~ 17.8) | < 0.001 | 0.027 OR 0.994 |
Hemoglobin (g/L) | 132.66 ± 17.44 | 127.69 ± 20.72 | < 0.001 | n.s |
Leukocyte | 9.47 ± 3.99 | 7.15 ± 3.20 | 0.280 | |
Neutrophil | 59.05 ± 12.15 | 61.31 ± 14.91 | 0.006 | n.s |
Eosinophil | 2.02 ± 1.72 | 1.73 ± 1.72 | 0.708 | |
Basophil | 0.51 ± 0.46 | 0.61 ± 0.47 | 0.688 | |
Lymphocyte | 30.24 ± 11.15 | 30.18 ± 12.85 | 0.715 | |
Monocyte | 7.93 ± 2.88 | 8.20 ± 3.43 | 0.056 | |
Serum ferritin | 144.67 ± 135.41 | 306.94 ± 198.77 | 0.002 | n.s |
Platelet | 240.81 ± 82.84 | 240.81 ± 158.00 | 0.995 | |
BDCAF | 2.86 ± 0.765 | 3.20 ± 1.07 | < 0.001 | 0.010 OR 0.590 |