Characteristics | BD patients with isolated upper gastrointestinal ulcer | BD patients with isolated ileocecus ulcer | P |
---|---|---|---|
Number of patients | n = 84 | n = 106 | |
Demographics | |||
Gender (M/F) | 55/29 | 56/50 | 0.054 |
Age at onset (years, mean±SD) | 32.99 ± 14.36 | 27.33 ± 14.63 | 0.008 |
Duration (months, mean±SD) | 108.70 ± 100.32 | 114.72 ± 122.27 | 0.716 |
Clinical manifestations | |||
Extraintestinal manifestations | |||
Oral ulcers n (%) | 84 (100) | 106 (100) | |
Genital ulcers n (%) | 57 (67.86) | 71 (66.98) | 0.512 |
Skin lesions n (%) | 42 (50) | 38 (35.85) | 0.035 |
Ocular lesions n (%) | 5 (5.95) | 6 (5.66) | 0.343 |
Neurologic lesions n (%) | 0 (0) | 7 (6.60) | 0.015 |
Cardiac valvular lesions n (%) | 1 (1.19) | 0 (0) | 0.442 |
Venous thrombosis n (%) | 3 (3.57) | 2 (1.89) | 0.391 |
Aneurysms n (%) | 3 (3.57) | 1 (0.94) | 0.229 |
Gastrointestinal complications | |||
Hemorrhage n (%) | 7 (8.33) | 15 (14.15) | 0.155 |
Perforation n (%) | 0 (0) | 9 (8.49) | 0.004 |
Obstruction n (%) | 0 (0) | 7 (6.60) | 0.015 |
History of surgery n (%) | 1 (1.19) | 11 (10.38) | 0.008 |
Assistant examination | |||
ESR (mm/h) | 18 (7.25~28.75) | 16 (7.50~40.00) | 0.580 |
CRP (mg/L) | 8.55 (3.19~10.00) | 10 (3.68~19.65) | 0.167 |
Leukocyte | 6.06 ± 2.39 | 7.55 ± 3.18 | 0.084 |
Neutrophil | 57.54 ± 15.38 | 63.11 ± 14.33 | 0.463 |
Eosinophil | 2.36 ± 2.16 | 2.53 ± 1.48 | 0.220 |
Basophil | 0.475 ± 0.37 | 0.47 ± 0.39 | 0.401 |
Lymphocyte | 32.03 ± 12.62 | 26.43 ± 12.53 | 0.851 |
Monocyte | 7.59 ± 3.03 | 8.35 ± 3.49 | 0.522 |
Platelet | 231.91 ± 72.00 | 247.07 ± 89.09 | 0.277 |
Serum ferritin | 185.31 ± 42.49 | 185.40 ± 44.17 | 0.985 |
BDCAF | 3.28 ± 0.924 | 3.22 ± 1.146 | 0.100 |
Pathological findings | 0.055 | ||
Vasculitis n (%) | 0 (0) | 2 (2.67) | |
Granuloma n (%) | 9 (15.25) | 21 (28.00) | |
Inflammatory infiltration n (%) | 50 (84.75) | 52 (69.33) |