Skip to main content

Table 3 Changes in lung volumes measured by CT before and on nintedanib treatment (N = 9)

From: Nintedanib in idiopathic and secondary pleuroparenchymal fibroelastosis

Lung volume measurement

Before nintedanib

On nintedanib

P value

Duration of CT follow-up (days)

361 ± 429 (range: 92–1277)

452 ± 357 (range: 120–1247)

0.575

Δ LUL volume (mL/year)

− 125 ± 211

− 90 ± 125

0.575

Δ LLL volume (mL/year)

− 83 ± 218

− 42 ± 123

0.575

Δ RUL volume (mL/year)

− 107 ± 210

− 58 ± 56

0.484

Δ RML volume (mL/year)

− 36 ± 92

− 12 ± 51

0.889

Δ RLL volume (mL/year)

+ 155 ± 662

− 86 ± 98

0.575

Δ carinal surface/year

+ 9.07 ± 139

+ 52 ± 70

0.401

Δ APDT (mL/year)

− 14.8 ± 21

− 6.5 ± 20

0.401

ΔTDT (mL/year)

− 306 ± 1113

− 2.86 ± 9.23

0.889

  1. APDT: anteroposterior diameter of the thoracic cage, LLL: left lower lobe, LUL: left upper lobe, RLL: right lower lobe, RML: right middle lobe, RUL: right upper lobe, TDT: transthoracic diameter of the thoracic cage