Table 1 Subject demographics and baseline characteristics
High-dose PXT3003a | Low-dose PXT3003 | Placebo | ||||
|---|---|---|---|---|---|---|
FAS | mFAS | FAS | mFAS | FAS | mFAS | |
(N = 113) | (N = 55) | (N = 109) | (N = 93) | (N = 101) | (N = 87) | |
CMTNS-v2b | 13.68 (3.19) | 13.02 (3.25) | 14.13 (3.04) | 14.04 (2.99) | 13.94 (3.13) | 14.01 (3.27) |
ONLS score | 3.18 (1.11) | 3.05 (1.13) | 3.39 (1.05) | 3.33 (1.05) | 3.20 (1.17) | 3.23 (1.19) |
Age (years) | 39.6 (13.9) | 41.2 (13.6) | 41.0 (12.3) | 40.7 (12.4) | 42.1 (13.2) | 42.3 (13.2) |
BMI (kg/m2) | 25.2 (4.52) | 24.9 (4.53) | 25.6 (4.72) | 25.4 (4.68) | 25.4 (4.94) | 25.2 (4.90) |
Sex (n, [%]) | ||||||
Female | 68 (60.2) | 34 (61.8) | 60 (55.0) | 51 (54.8) | 62 (61.4) | 51 (58.6) |
Male | 45 (39.8) | 21 (38.2) | 49 (45.0) | 42 (45.2) | 39 (38.6) | 36 (41.4) |
Race (n, [%]) | ||||||
White | 110 (97.3) | 53 (96.4) | 107 (98.2) | 91 (97.8) | 100 (99.0) | 86 (98.9) |
Black | 1 (0.9) | 1 (1.8) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 0 (0.0) |
Asian | 2 (1.8) | 1 (1.8) | 2 (1.8) | 2 (2.2) | 1 (1.0) | 1 (1.1) |