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Table 1 Internal consistency reliability estimates of biweekly ISM-SAF domain and total scores

From: Psychometric evaluation of the Indolent Systemic Mastocytosis Symptom Assessment Form (ISM-SAF) in a phase 2 clinical study

Domain/total score Cronbach's alpha
Baseline N = 38 C3D1 N = 37 C4D1 N = 36
Total symptom score 0.86 0.85 0.86
Alpha if item deleted
Q1. Bone pain 0.84 0.84 0.84
Q2. Abdominal pain 0.83 0.83 0.84
Q3. Nausea 0.84 0.83 0.84
Q4. Spots 0.88 0.88 0.89
Q5. Itching 0.84 0.83 0.84
Q6. Flushing 0.85 0.84 0.85
Q7. Fatigue 0.84 0.83 0.84
Q8. Dizziness 0.83 0.83 0.84
Q9. Brain fog 0.84 0.83 0.84
Q10.Headache 0.85 0.84 0.85
Q12. Diarrhea severity 0.84 0.85 0.86
Gastrointestinal Symptom Score 0.83 0.73 0.72
Alpha if item deleted
Q2. Abdominal pain 0.63 0.37 0.44
Q3. Nausea 0.73 0.55 0.44
Q12. Diarrhea severity 0.91 0.88 0.90
Skin Symptom Score 0.82 0.76 0.76
Alpha if item deleted
Q4. Spots 0.87 0.79 0.83
Q5. Itching 0.63 0.61 0.52
Q6. Flushing 0.73 0.63 0.64
  1. C#D# cycle number, day number, ISM-SAF Indolent Systemic Mastocytosis Symptom Assessment Form