Fig. 2From: Clinical, imaging, biochemical and molecular features in Leigh syndrome: a study from the Italian network of mitochondrial diseasesMRI findings. Graph depicts frequency of brain MRI involved regions in our LS cohort (A). Supratentorial pattern: axial (B) and coronal (C) T2WI sequences show hyperintensities of putamen in a patient with complex I deficiency associated to MT-ND3; supra and subtentorial pattern: coronal (D) and sagittal (E) T2WI sequences show hyperintensities in subthalami (D) and brainstem (E) in a patient with complex IV deficiency associated to SURF1; subtentorial pattern: coronal T2WI (F) and FLAIR (G) show hyperintensities (F) and cavited pattern (G) in dentate nuclei in a patient with complex I deficiency associated to NDUFAF6Back to article page