Modifiable factors affecting renal preservation in type I glycogen storage disease after liver transplantation: a single-center propensity-match cohort study

Table 2 The development of estimated glomerular filtration rate (eGFR, ml/min/1.73 m²) over the years

LT No	GSD type	Gene	Mutation	Pre GFR	1y GFR	2y GFR	3y GFR	4y GFR	5y GFR	6y GFR	7y GFR	8y GFR	9y GFR	10y GFR	11y GFR	12y GFR	13y GFR	14y GFR	15y GFR	16y GFR	17y GFR	18y GFR	19y GFR	20y GFR	21y GFR	22y GFR
18	Ia	G6PC	c.727G-> T/c.727G-> T	58	73	76	63	106	86	85	60	50*	28^#	22	14	11	5	4	3	4^@	NA	NA	NA	NA	19	17
27	Ib	SLC37A4	p.R300C/undetected	127	104	64	93	125	102	88	94	98	86	116	121	107	104	130	140	167	142	132	153	139	122	116
28	Ia	G6PC	p.I341N/c.727G-> T	93	73	54	51	66	72	67^#	46*	59	76	85	74	73	63	68	62	62	63	65	58	55	56	53
164	Ia	G6PC	p.R83H/c.727G-> T	135	158	85	77	82	128	126	117	130	132	103	122	107	112	90	90	111
215	Ia	G6PC	p.H119L/c.727G-> T	117	55	107	94	112	126	128	179	150	154	196	175	155	168	134	144
235	Ia	G6PC	p.R83H/p.I341N	104	83	76	102	114	110	109	119	115	122	98	104	107	106	98	97
244	Ia	G6PC	c.727G-> T/c.727G-> T	98	86	79	99	108	100	94	81	82	92	119	117	130	117	124	108
281	Ia	G6PC	c.727G-> T/c.727G- > T	85	116	87	138	154	161	182	152	132	162	167	214	150	146	175
1344	Ia	G6PC	p.R83H/c.727G-> T	130	146*	143	158	128

^*Time point of shifting calcineurin inhibitor (CNI) to mammalian target of rapamycin (mTOR) inhibitor
^#Time point of occurrence of de novo hypertension
^@Time point of cadaveric renal transplantation

ISSN: 1750-1172