From: Variables affecting pricing of orphan drugs: the Italian case
Cluster | Prevalence | Number of medicines | ASMR | RCT | Annual treatment cost (€) | Regression coefficient, 95% confidence interval |
---|---|---|---|---|---|---|
1 | Low | 13 | Mean: 3.77 | Yes | 294,514 | |
2 | Low | 11 | Mean: 3.91 | No | 107,297 | − 1.06 (− 1.82, − 0.31) |
3 | High | 6 | Mean: 3.83 | No | 187,370 | − 0.21 (− 1.12, 0.69) |
4 | High | 22 | Mean: 4.09 | Yes | 63,855 | − 1.26 (− 1.9, − 0.62) |