Table 6 Results of DIF analyses of PNH versus general population
Item | Label | Domain | DIF by Group (PNH vs. general population) | |||||
|---|---|---|---|---|---|---|---|---|
Test of uniform DIF | Test of non-uniform DIF | |||||||
Likelihood ratio test p value | "Favored" group | Odds ratio on group effect | Likelihood ratio test p value | "Favored" group at the mean total domain score | Odds ratio on group effect at the mean total domain score | |||
eortc29 | 29. How would you rate your overall health during the past week? | Global | NS | NS | NS | NS | NS | NS |
eortc30 | 30. How would you rate your overall quality of life during the past week? | Global | NS | NS | NS | NS | NS | NS |
eortc01 | 1. Do you have any trouble doing strenuous activities, like carrying a heavy shopping bag or a suitcase? | Physical | p < .001 | General pop | 0.5326 | p = .0214 | General pop | 0.5599 |
eortc02 | 2. Do you have any trouble taking a long walk? | Physical | p < .001 | Ecu/Ravu | 1.9937 | NS | NS | NS |
eortc03 | 3. Do you have any trouble taking a short walk outside of the house? | Physical | NS | NS | NS | NS | NS | NS |
eortc04 | 4. Do you need to stay in bed or a chair during the day? | Physical | NS | NS | NS | p = .0089 | Ecu/Ravu | 1.0833 |
eortc05 | 5. Do you need help with eating, dressing, washing yourself or using the toilet? | Physical | NS | NS | NS | NS | NS | NS |
eortc06 | 6. Were you limited in doing either your work or other daily activities? | Role | NS | NS | NS | NS | NS | NS |
eortc07 | 7. Were you limited in pursuing your hobbies or other leisure time activities? | Role | NS | NS | NS | NS | NS | NS |
eortc21 | 21. Did you feel tense? | Emotional | p < .001 | General pop | 0.2567 | NS | NS | NS |
eortc22 | 22. Did you worry? | Emotional | NS | NS | NS | p < .001 | Ecu/Ravu | 1.3910 |
eortc23 | 23. Did you feel irritable? | Emotional | p < .001 | Ecu/Ravu | 2.8577 | NS | NS | NS |
eortc24 | 24. Did you feel depressed? | Emotional | p < .001 | General pop | 0.5886 | p < .001 | General pop | 0.7189 |
eortc20 | 20. Have you had difficulty in concentrating on things, like reading a newspaper or watching television? | Cognitive | p < .001 | General pop | 0.2165 | p < .001 | General pop | 0.1177 |
eortc25 | 25. Have you had difficulty remembering things? | Cognitive | p < .001 | Ecu/Ravu | 1.9155 | p < .001 | Ecu/Ravu | 1.6161 |
eortc26 | 26. Has your physical condition or medical treatment interfered with your family life? | Social | p < .001 | General pop | 0.3198 | p = .0003 | General pop | 0.5326 |
eortc27 | 27. Has your physical condition or medical treatment interfered with your social activities? | Social | p < .001 | General pop | 0.3135 | p < .001 | General pop | 0.1755 |
eortc10 | 10. Did you need to rest? | Fatigue | p < .001 | General pop | 0.3642 | NS | NS | NS |
eortc12 | 12. Have you felt weak? | Fatigue | NS | NS | NS | NS | NS | NS |
eortc18 | 18. Were you tired? | Fatigue | p < .001 | Ecu/Ravu | 2.4351 | p < .001 | Ecu/Ravu | 2.4843 |
eortc14 | 14. Have you felt nauseated? | Nauseau | p = .0253 | Ecu/Ravu | 1.8589 | p < .001 | General pop | 0.4916 |
eortc15 | 15. Have you vomited? | Nauseau | p = .0006 | General pop | 0.1791 | NS | NS | NS |
eortc09 | 9. Have you had pain? | Pain | p < .001 | General pop | 0.3012 | NS | NS | NS |
eortc19 | 19. Did pain interfere with your daily activities? | Pain | NS | NS | NS | p < .001 | Ecu/Ravu | 1.4191 |