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Table 4 Liver transplant cohort and main disease categories leading to transplantation

From: The frequency of rare and monogenic diseases in pediatric organ transplant recipients in Italy

Disease macro-category

Pediatrics (n. 1,037)

Adults (n. 15,836)

Total (n. 16,873)

n. (%)

n. (%)

n. (%)

Hepatopathies from atresia of the biliary tract

433 (41.8)

32 (0.2)

465 (2.8)

Metabolic diseases

126 (12.2)

350 (2.2)

476 (2.8)

Cholestatic cirrhosis and other cholestatic liver diseases

121 (11.7)

857 (5.4)

978 (5.8)

Neoplasia

83 (8.0)

4,505 (28.4)

4,588 (27.2)

Acute liver necrosis

44 (4.2)

404 (2.6)

448 (2.7)

Other non-cholestatic cirrhosis

43 (4.1)

5,950 (37.6)

5,993 (35.5)

HBV/HCV related cirrhosis

5 (0.5)

1,116 (7.0)

1,121 (6.6)

Alcoholic cirrhosis

0 (0.0)

1,686 (10.6)

1,686 (10.0)

Other hepatopathies

182 (17.5)

936 (5.9)

1,118 (6.6)