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Table 3 Functional abilities by median age

From: PACS1-Neurodevelopmental disorder: clinical features and trial readiness

Level Median age in years (IQR) P value (DF)a
Communication   0.10 (4, 23)
Effectively communicates with everyone (N = 1, 4%) 3  
Effectively communicates with adults (N = 11, 39%) 8 (4.5–11, max = 12.5)  
Effectively communicates with familiar people (N = 7, 25%) 15.5 (7–16, max = 19)  
Inconsistently communicates (N = 7, 25%) 13 (9–15, max = 26)  
Seldom communicates (N = 2, 7%) 4 (3.5–5, max = 6)  
Fine motor   0.42 (1, 29)
Holds large objects (N = 4, 13%) 7 (2–12, max = 15.5)  
Pincer grasp (N = 27, 87%) 8 (5.5–14, max = 26)  
Gross motor   0.83b
Spearman correlation between age and FAQ score (N = 30) rs = -0.04  
Academic skills   0.09 (1, 27)
Yes (N = 16, 55%) 11 (7.5–13.7, max = 26)  
No (N = 13, 45%) 5.83 (3–8, max = 19)  
Autism diagnosis   0.63 (2, 28)
Diagnosis (N = 12, 39%) 9.5 (5.5–11.5, max = 16.5)  
Features (N = 11, 35%) 13 (6.5–15, max = 18.5)  
No diagnosis (N = 8, 26%) 5.5 (3–10.5, max = 26)  
Epilepsy diagnosis   0.05 (1, 30)
Yes (N = 17, 53%) 9 (7–16.5, max = 26)  
No (N = 15, 47%) 5 (3.5–11, max = 15.5)  
Toileting   0.24 (2, 25)
Independent (N = 7, 25%) 11.5 (8–14.5, max = 16.5)  
Partially dependent (N = 11, 39%) 11 (7–13, max = 26)  
Completely dependent (N = 10, 36%) 5 (4–11, max = 15.5)  
Eating   0.06 (3, 25)
Independent (N = 15, 52%) 11 (5.5–14.5, max = 26)  
Some assistance (N = 8, 28%) 12 (8–15, max = 19)  
Considerable assistance (N = 2, 7%) 5.5 (4–6.5, max = 8)  
Dependent (N = 4, 14%) 3.3 (2–4, max = 6)  
Nocturnal awakenings   0.46 (5, 24)
6–7 nights/week (N = 1, 4%) 15  
3–5 nights/week (N = 3, 12%) 8 (6.5–9.5, max = 11)  
1–2 nights/week (N = 7, 27%) 6 (4–9.5, max = 13)  
< 1 night/week (N = 5, 19%) 8 (3–11, max = 16.5)  
Never (N = 10, 39%) 11 (8–15.5, max = 26)  
  1. aOne way analysis of variance was used to obtain P values
  2. bSpearman correlation