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Fig. 4 | Orphanet Journal of Rare Diseases

Fig. 4

From: Monogenic mutations in four cases of neonatal-onset watery diarrhea and a mutation review in East Asia

Fig. 4

H&E staining of intestinal biopsies from Patients 2–4. A Villus flattening, disorganized epithelium in the duodenum biopsy from Patient 2 (400×). B Villus atrophy with crowded epithelial cells in the terminal ileal mucosal biopsy from Patient 2 (200×). C Chronic inflammation; villous atrophy in the colon from Patient 2 (200×). D Normal villous height in the ileum from Patient 3 (200×). E Hyperemia, edema, and lymphocyte aggregates in the colon from Patient 3 (200×). F Hyperemia, edema, and prominent lymphocyte infiltration; villous blunting in duodenum from Patient 4 (200×)

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