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Table 3 Logistic regression model on the association between different variables and the odds of hospital mortality before and during the COVID-19 pandemic

From: Hospital mortality in patients with rare diseases during pandemics: lessons learnt from the COVID-19 and SARS pandemics

Factors

Crude OR

95% C.I.

p value

Adjusted ORa

Adjusted 95% C.I.a

Adjusted p valuea

Rare disease

 No (general population)

1.00

1.00

 Yes

1.67

1.60–1.74

< 0.001

2.06

1.98–2.16

< 0.001

Age

 ≤ 18

1.00

1.00

 19–59

8.41

7.52–9.76

< 0.001

8.61

7.42–9.99

< 0.001

 ≥ 60

60.66

52.43–70.18

< 0.001

62.24

53.79–72.01

< 0.001

Time period

 Admitted one year before pandemic (2019)

1.00

1.00

 Admitted with COVID-19 infection during pandemic period (2020)

0.44

0.36–0.55

< 0.001

0.72

0.58–0.89

0.002

 Admitted without COVID-19 infection during pandemic period (2020)

1.26

1.24–1.29

< 0.001

1.22

1.20–1.25

< 0.001

  1. C.I. confidence interval, COVID-19 coronavirus disease of 2019, OR odds ratio
  2. aAdjusted for each and all of the variables in the table